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Protein NBS1 is crucial for macrophage functional activity

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Protein NBS1, which plays a key role in DNA damage repair, is required for macrophage functional activity. This is one of the conclusions of a scientific paper published in the journal Blood by a team of experts from the Faculty of Biology of the University of Barcelona (UB), the Barcelona Science Park (PCB) and the Institute for Research in Biomedicine (IRB Barcelona). The protein also has implications for understanding the immune defects observed in patients with Nijmegen breakage syndrome and other related disorders.

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